Why Omega-3 Fatty Acids Are So Important
Omega-3 fatty acids are among the most important nutrients for our health. They support heart function, reduce inflammation and are important for brain function. Since our body cannot produce them itself, we must obtain them through diet or supplements.
Key Points at a Glance
- EPA (Eicosapentaenoic acid): Important for heart health and anti-inflammation
- DHA (Docosahexaenoic acid): Essential for brain and eye function
- Molecular distillation: Removes heavy metals and contaminants
- Triglyceride form: Better bioavailability than ethyl esters
Scientifically Proven Benefits of Omega-3
Heart Health
Reduces triglycerides, supports normal heart function and may prevent heart rhythm disorders.
Brain Function
DHA is important for memory, concentration and may protect against age-related cognitive decline.
Anti-inflammatory
EPA reduces inflammatory markers in the body and may help with chronic inflammation.
Eye Health
DHA is an important building block of the retina and may protect against age-related macular degeneration.
Our Test Criteria for Omega-3 Supplements
When evaluating Omega-3 supplements, we particularly focused on quality, purity and scientific evidence:
EPA/DHA Content
Concentration of active Omega-3 fatty acids per capsule
Purity
Freedom from heavy metals, PCBs and other contaminants
Bioavailability
Triglyceride form vs. ethyl esters - how well does the body absorb it?
Certifications
IFOS, MSC or other independent quality certificates
The Top 10 Omega-3 Supplements 2025 in Test

1. Nordic Naturals Ultimate Omega
The gold standard among Omega-3 supplements. Highest purity, optimal triglyceride form and award-winning quality.
Pros
- Highest purity and quality
- Triglyceride form for best absorption
- IFOS 5-star certified
- Sustainable fishing (MSC)
Cons
- Premium price
- Large capsules
Dosage & Intake
Recommendation: 2 capsules daily with meals. Each capsule contains 640mg EPA+DHA (410mg EPA, 230mg DHA).

2. San Omega-3 Total
Excellent value for money with high EPA+DHA concentration. German pharmaceutical quality at a fair price.

3. Life Extension Super Omega-3
Scientifically based formulation with additional lignans from sesame and olive extract for improved stability.
Detailed Comparison of Top 5
Product | EPA+DHA per Serving | Form | Certification | Price/Month | Rating |
---|---|---|---|---|---|
Nordic Naturals Ultimate | 1280mg | Triglyceride | IFOS 5★ | ~$22 | 9.6/10 |
San Omega-3 Total | 1000mg | Triglyceride | Pharma Quality | ~$14 | 9.1/10 |
Life Extension Super | 700mg | Triglyceride | GMP | ~$18 | 8.8/10 |
Omega-3 Zone | 900mg | Triglyceride | IFOS | ~$16 | 8.5/10 |
Norsan Omega-3 Total | 2000mg | Liquid | IFOS | ~$25 | 8.3/10 |
Dosage Recommendations for Omega-3
General Health
- EPA+DHA: 250-500mg daily
- Timing: With meals
- Duration: Long-term intake
Heart Health
- EPA+DHA: 1000-2000mg daily
- Ratio: EPA:DHA 2:1 to 3:1
- Control: Regular blood tests
Brain Function
- DHA: 400-1000mg daily
- Age: Especially important from 50+
- Combination: Makes sense with B vitamins
Sports & Inflammation
- EPA: 1000-2000mg daily
- Timing: After training
- Combination: With Vitamin E
Safety and Side Effects
Safe at Normal Dosage
- Up to 3g EPA+DHA daily is considered safe
- High-quality supplements are free from contaminants
- Natural nutrient with long history of use
Possible Side Effects
- Fishy taste or burping (rare with good quality)
- Blood-thinning effect at very high doses
- Interaction with blood thinners possible
Important Notes
- Pregnancy: DHA is important for baby's development - consult with gynecologist
- Allergies: For fish allergies, algae-based Omega-3 supplements are an alternative
- Medications: Consult your doctor before taking blood thinners
- Quality: Only choose products with purity certificate (IFOS, GOED)
Conclusion: The Best Omega-3 Supplement for You
Nordic Naturals Ultimate Omega sets the gold standard with highest quality and purity. For most people, it is the best choice, even though the price is higher.
San Omega-3 Total offers excellent German pharmaceutical quality at a fairer price and is our best value winner.
More important than the brand is regular intake: A mediocre supplement that you take daily is better than the best product sitting in the cupboard.